Affordable hotels in Rome with queen or twin beds under $300 (Sept 2025)

Accommodations in Italy for your September 2025 trip include well-rated hotels and guesthouses under $300 per night, located in good neighborhoods across Rome, Florence, Montepulciano, Palermo, Agrigento, Siracusa, and Sorrento. These options offer comfortable queen or twin beds, modern amenities, and convenient access to local attractions and transport.