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Best Hotels to Stay in Des Moines, Iowa to Sioux Falls, South Dakota
Traveling from Des Moines, Iowa to Sioux Falls, South Dakota, you can expect a range of hotels that cater to both business and leisure travelers. These accommodations typically offer modern amenities, complimentary breakfast, and easy access to local attractions such as parks, museums, and shopping areas.
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Hilton Garden Inn Sioux Falls South
5300 South Grand Circle, Sioux Falls SD 57108

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8.5
Very Good
(120 reviews)










Des Moines Marriott Downtown
700 Grand Avenue, Des Moines IA 50309

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8.3
Very Good
(99 reviews)










Hotel On Phillips
100 North Phillips Avenue, Sioux Falls SD 57104

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9.2
Wonderful
(375 reviews)










Hyatt Place Sioux Falls South
4935 W Lake Shore Blvd, Sioux Falls 57106

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9.1
Wonderful
(616 reviews)










Rocket Motel
211 Mt Rushmore Road, Custer SD 57730

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9.1
Wonderful
(445 reviews)