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Luxury 5-Star Hotels in Rome for 5 Adults (May 2025)
In Rome, you can expect a selection of luxury five-star hotels that offer opulent accommodations, fine dining, and exceptional service. Many of these hotels are located near iconic landmarks such as the Colosseum and the Vatican, providing easy access to the city's rich history and culture.
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95% Match
The St. Regis Rome
Via Vittorio Emanuele Orlando 3, 00185 Rome
Storied Collection:
This hotel offers **luxury** accommodation in Rome's historic centre, making it perfect for your stay. With spacious rooms and a health club and spa, it ensures a superior experience for all guests.
9.1
Wonderful
(161 reviews)
Matched amenities:
Restaurant
Pets allowed
Room serviceMeeting/banquet facilitiesBar
RestaurantPets allowedRoom serviceMeeting/banquet facilitiesBar/night
Available from:May 28-30
90% Match
Rome Cavalieri, A Waldorf Astoria Hotel
Via Cadlolo 101, 00136 Rome
Storied Collection:
This hotel offers a **luxurious** experience with spacious rooms and a stunning view of Rome. Enjoy the **wellness centre** and gourmet dining options, perfect for a lavish stay.
8.9
Very Good
(887 reviews)
Matched amenities:RestaurantPets allowedRoom serviceMeeting/banquet facilitiesBar
RestaurantPets allowedRoom serviceMeeting/banquet facilitiesBar/night
Available from:May 28-30
90% Match
Baglioni Hotel Regina - The Leading Hotels of the World
Via Vittorio Veneto 72, 00187 Rome
Storied Collection:
This hotel offers **luxurious** accommodations with elegant Art Deco style, perfect for a group of five. Enjoy the **wellness centre** with sauna and hot tub, ideal for relaxation after exploring Rome.
9.1
Wonderful
(1185 reviews)
Matched amenities:RestaurantPets allowedRoom serviceMeeting/banquet facilitiesBar
RestaurantPets allowedRoom serviceMeeting/banquet facilitiesBar/night
Available from:May 28-30
95% Match
Villa Agrippina Gran Meliá – The Leading Hotels of the World
Via Del Gianicolo 3, 00165 Rome
Storied Collection:
This hotel offers a **luxurious** experience with elegant interiors and a range of high-end facilities, including a wellness center and outdoor swimming pool. Its prime location near major attractions like St Peter’s Basilica makes it perfect for exploring Rome.
9.1
Wonderful
(450 reviews)
Matched amenities:RestaurantPets allowedRoom serviceMeeting/banquet facilitiesBar
RestaurantPets allowedRoom serviceMeeting/banquet facilitiesBar/night
Available from:May 28-30
90% Match
Hotel Palazzo Manfredi – Small Luxury Hotels of the World
Via Labicana 125, 00184 Rome
Storied Collection:
This hotel offers a **luxurious** experience with spacious rooms and a stunning view of the Coliseum from the rooftop terrace. With its **central location**, you can easily explore Rome's historic sites, making it perfect for your stay.
8.6
Very Good
(593 reviews)
Matched amenities:RestaurantRoom serviceMeeting/banquet facilitiesBar24-hour front desk
RestaurantRoom serviceMeeting/banquet facilitiesBar24-hour front desk/night
Available from:May 28-30