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Unique boutique hotels in Rome for a memorable stay (April 2025)
In Rome, you can expect a variety of unique boutique hotels that offer personalized service and distinctive decor, often reflecting the city's rich history and culture. Many of these accommodations are located near iconic landmarks such as the Colosseum, Vatican City, and charming piazzas, providing easy access to local amenities and attractions.
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The Fifteen Keys Hotel
Via Urbana 6-7, 00184 Rome

Storied Collection:
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9.4
Wonderful
(348 reviews)










Flaminio Village Bungalow Park
Via Flaminia Nuova 821, 00189 Rome

Storied Collection:
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7.7
Good
(5406 reviews)










My Rhome Prati
Via Vigliena 2, 00192 Rome

Storied Collection:
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8.8
Very Good
(346 reviews)










Precise House Mantegna Roma
Via Mantegna 130, 00147 Rome

Storied Collection:
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8.6
Very Good
(1457 reviews)










Five Rooms Rome Guesthouse
Via Della Consulta 1/B, 00184 Rome

Storied Collection:
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8.6
Very Good
(784 reviews)