Ask Layla AI
Route 66 Adventure: Chicago to Los Angeles Itinerary (Aug 2025)
Traveling along Route 66 from Chicago to Los Angeles offers a mix of vibrant city life and stunning natural landscapes. Expect to find a variety of accommodations ranging from classic motels to modern hotels, with local amenities including diners, roadside attractions, and access to national parks like the Grand Canyon and Petrified Forest.
Powered by










The Hollywood Roosevelt
7000 Hollywood Boulevard, Los Angeles CA 90028

Storied Collection:
... Read more
8.3
Very Good
(3266 reviews)










citizenM Chicago Downtown
80 East Wacker Place, Chicago IL 60601

Storied Collection:
... Read more
8.9
Very Good
(3593 reviews)










Desert Rose Resort
5051 Duke Ellington Way, Las Vegas NV 89119

Storied Collection:
... Read more
8.8
Very Good
(5675 reviews)










Jockey Club Suites
3700 Las Vegas Boulevard South, Las Vegas NV 89109

Storied Collection:
... Read more
8.7
Very Good
(3689 reviews)










Trump International Hotel Las Vegas
2000 Fashion Show Drive, Las Vegas NV 89109

Storied Collection:
... Read more
8.7
Very Good
(8318 reviews)
Previous Searches
Route 66 Adventure: Chicago to Los Angeles Itinerary (Aug 2025) - Restaurantes y museos en Villa de Leyva para un viaje corto - Camping in Halkidiki: Kasandra & Sithonia Beach Adventure - Hotéis em Milão com minibar por 400€ (11-14 setembro 2024) - 6-Day NYC Itinerary: Explore Upper West Side to Hudson Yards - Guía turística de La Paz y pueblos mágicos (15-22 Septiembre) - Winter Wonderland Getaways from Miami (December-January) - Clean hotels in Denpasar with AC & breakfast options (Aug 29-30, 2024) -