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Wheelchair Accessible Hotels on Route 66 from Chicago to Los Angeles (September 2025)
Along Route 66, travelers can expect a variety of accommodations ranging from vintage motels to modern hotels, many of which offer wheelchair-accessible rooms and amenities. The route is dotted with charming small towns, local diners, and iconic landmarks, ensuring a memorable journey with convenient access for all.
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85% Match
LondonHouse Chicago, Curio Collection by Hilton
85 East Wacker Drive , Chicago IL 60601
Storied Collection:
This hotel offers **wheelchair accessibility** and is located in a prime area near the Chicago River, making it a great starting point for your Route 66 journey. With spacious guest rooms and a 24-hour fitness center, it ensures a comfortable stay before you hit the road.
9.0
Very Good
(882 reviews)
Matched amenities:
Parking
Restaurant
Room serviceMeeting/banquet facilitiesBar
ParkingRestaurantRoom serviceMeeting/banquet facilitiesBar/night
Available from:Sep 23-30
85% Match
Drury Inn & Suites St. Louis Forest Park
2111 Sulphur Avenue, Saint Louis MO 63139
Storied Collection:
This hotel offers **wheelchair accessibility** and is conveniently located just off Interstate 44, making it a great stop along Route 66. Guests can enjoy a complimentary hot breakfast and relax in the indoor pool or hot tub after a long day of travel.
9.0
Very Good
(557 reviews)
Matched amenities:
Facilities for disabled guests
Wheelchair accessibleToilet with grab railsHigher level toiletLower bathroom sink
Facilities for disabled guestsWheelchair accessibleToilet with grab railsHigher level toiletLower bathroom sink/night
Available from:Sep 23-30
85% Match
Best Western Plus Inn of Williams
2600 West Route 66 , Williams AZ 86046
Storied Collection:
This hotel offers **wheelchair accessible** facilities and is located on the iconic Route 66, making it a perfect stop for your journey. Enjoy the outdoor heated pool and hot tub, along with a daily hot breakfast buffet to start your day right!
8.8
Very Good
(939 reviews)
Matched amenities:Facilities for disabled guestsWheelchair accessibleToilet with grab railsHigher level toiletLower bathroom sink
Facilities for disabled guestsWheelchair accessibleToilet with grab railsHigher level toiletLower bathroom sink/night
Available from:Sep 23-30
85% Match
Chicago Marriott Downtown Magnificent Mile
540 North Michigan Avenue, Chicago IL 60611
Storied Collection:
This hotel is **wheelchair accessible** and located in the heart of downtown Chicago, making it a perfect starting point for your Route 66 journey. With a state-of-the-art **fitness centre** and on-site dining options, you'll have everything you need for a comfortable stay before hitting the road.
8.1
Very Good
(453 reviews)
Matched amenities:ParkingRestaurantRoom serviceMeeting/banquet facilitiesBar
ParkingRestaurantRoom serviceMeeting/banquet facilitiesBar/night
Available from:Sep 23-30
75% Match
HI Los Angeles Santa Monica Hostel
1436 2nd Street, Los Angeles CA 90401
Storied Collection:
This hostel is centrally located near the beaches of Santa Monica and offers **easy access** to various attractions along Route 66. With a fully stocked guest kitchen and a private courtyard, it provides a comfortable and convenient stay for travelers.
8.9
Very Good
(5391 reviews)
Matched amenities:Meeting/banquet facilities24-hour front desk
GardenNon-smoking roomsFacilities for disabled guests
Meeting/banquet facilities24-hour front deskGardenNon-smoking roomsFacilities for disabled guests/night
Available from:Sep 23-30