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The route from Gainesville, Florida to Lyme, New Hampshire along I-95 passes through several major cities including Savannah, GA, and Washington, DC. Accommodations along this route typically include budget to midrange hotels that offer convenient access to the highway, free WiFi, parking, and basic amenities suitable for a comfortable overnight stay during a road trip.

Gainesville

Lyme

Featuring 2-star accommodation, Quality Inn Gainesville I-75 is located in Gainesville, 7 km from University of Florida and 8.4 km from Ben Hill Griffin Stadium. The property is around 6.7 km from Regal Cinemas Royal Park Stadium 16, 23 km from Gainesville Raceway and 47 km from Ginnie Springs. The inn provides an outdoor swimming pool and free WiFi throughout the property.

At the inn, every room has a desk. All units in Quality Inn Gainesville I-75 are equipped with a TV and a hairdryer.

Florida Museum of Natural History and Butterfly Rainforest is 4 km from the accommodation, while Kanaphaha Botanical Gardens is 5.4 km away. Gainesville Regional Airport is 14 km from the property.

Quality Inn Gainesville I-75

This hotel near I-75 in Gainesville, FL, offers clean, comfortable rooms with friendly staff and convenient access to the interstate. Guests appreciate the quiet environment, safety, and complimentary breakfast, though some mention limited breakfast options and occasional noise.

Sherri

Steve

Robert

LaTasha

Wilkinson

David

Glenn

The location is great being just off the interstate.

Melissa

The clerk. who I believe is the manager, was extremely friendly and helpful.

Beltzer

quiet, clean and comfortable, would stay again,

Mary

Located off Interstate 75, this hotel is 2 miles from Santa Fe College.  It features a free airport shuttle and an on-site restaurant.  Every guest room offers free Wi-Fi.

A cable TV and in-room coffee are standard for all rooms at Best Western Gateway Grand.  The spacious rooms include a work desk and a clock radio.

Guests can relax at the hotel’s outdoor pool and hot tub or work out in the on-site fitness room.  Business facilities and meeting rooms are also available.

Gator’s Den features an extensive menu of classic American food and offers a full bar.  A free breakfast is provided daily.

Florida Museum of Natural History and the University of Florida are within a 15-minute drive of this hotel.  Devil’s Millhopper Geological State Park is 6 miles away.

Best Western Gateway Grand

Offering a daily hot breakfast buffet every morning and an outdoor pool on site, this pet-friendly Gainesville hotel is only 4.8 km from the University of Florida. Free WiFi is also included in all rooms.

Satellite TV is featured in each of the traditionally decorated rooms of the hōm hotel + suites along with an extra seating area.

Guests can work out in the 24-hour fitness centre at the Gainesville hōm hotel + suites or use the hotel’s meeting facilities. A launderette is also available on site.

This hotel is located off Interstate 75, just 10 minutes’ drive from Gainesville city centre. The Ben Hill Griffin Stadium is located 6.4 km away.

HoM, A Trademark Collection Hotel

Sleep Inn & Suites University/Shands is 4.7 km from Malcom Randall VA Medical Center and 5.1 from Shands Hospital at the University of Florida. Guests can start their day with a complimentary breakfast and then take a dip in the pool. Complimentary WiFi is provided for all guests.

All guest rooms come equipped with microwaves, coffee makers with free coffee, and refrigerators. A 32-inch flat-screen TV is offered. Pillow-top mattresses, hair dryers, and ironing facilities are provided. Some rooms feature sofa beds. A work desk is provided in all rooms.

Sleep Inn & Suites University/Shands features a fitness centre. Business guests will enjoy the convenience of a 24-hour business center, as well as copy and fax services. Guest laundry facilities are also provided. Valet cleaning services are available on the premises for added guest convenience. Parking is provided and can accommodate most trucks, RVs, buses and cars.

Ben Hill Griffin Stadium, home of the Florida Gators, is 6.7 km away. The Stephen C. O'Connell Center is 6.5 km from the property. Gainesville Regional Airport is a 19 minutes' drive from the property.

Sleep Inn & Suites University-Shands

Set within 3.7 km of University of Florida and 5.1 km of Ben Hill Griffin Stadium, Comfort Suites Gainesville Near University features rooms in Gainesville. With free WiFi, this 3-star hotel has an outdoor swimming pool and a fitness centre. The accommodation offers free shuttle service and a 24-hour front desk for guests.

All guest rooms at the hotel come with a seating area, a TV and a safety deposit box. The rooms will provide guests with a fridge.

Comfort Suites Gainesville Near University offers a buffet or American breakfast.

Regal Cinemas Royal Park Stadium 16 is 9.1 km from the accommodation, while Gainesville Raceway is 20 km from the property. Gainesville Regional Airport is 12 km away.

Comfort Suites Gainesville Near University

Budget to midrange hotels near I-95 from Gainesville, FL to Lyme, NH (July 2025)

Budget to midrange hotels near I-95 from Gainesville, FL to Lyme, NH

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Parking

Restaurant

Pets allowed

Room service

Meeting/banquet facilities

24-hour front desk

Tennis court

Sauna

Fitness centre

Golf course (within 3 km)

Garden

Terrace

Non-smoking rooms

Airport shuttle

Fishing

Business centre

Babysitting/child services

Laundry

Dry cleaning

Continental breakfast

Facilities for disabled guests

Skiing

Barber/beauty shop

Family rooms

Games room

Casino

Breakfast in the room

Ironing service

Free parking

Internet services

Lift

Express check-in/check-out

Solarium

Safety deposit box

Valet parking

Currency exchange

Spa and wellness centre

Massage

Children's playground

Billiards

Table tennis

Karaoke

Windsurfing

Darts

Hot tub/Jacuzzi

Soundproof rooms

Canoeing

Hiking

Chapel/shrine

BBQ facilities

Packed lunches

Car hire

Cycling

Bowling

Tour desk

Hammam

Heating

Fax/photocopying

Diving

Horse riding

Squash

Snorkelling

Luggage storage

WiFi

Mini golf

Ski storage

Ski school

Allergy-free room

Indoor pool

Outdoor pool

Free WiFi

Non-smoking throughout

Air conditioning

Designated smoking area

ATM/cash machine on site

Private beach area

Restaurant (à la carte)

Restaurant (buffet)

Snack bar

Sun terrace

Outdoor pool (all year)

Outdoor pool (seasonal)

Indoor pool (all year)

Indoor pool (seasonal)

Concierge service

Entertainment staff

Nightclub/DJ

Private check-in/check-out

Shuttle service (free)

Shuttle service (additional charge)

Ski equipment hire on site

Ski pass vendor

Ski-to-door access

Special diet menus (on request)

Trouser press

Vending machine (drinks)

Vending machine (snacks)

Water sport facilities on site

Hot spring bath

General

Activities

Services

Room Amenities

Bathroom

Media & Technology

Food & Drink

Services & Extras

Outdoor & View

Internet

Kitchen

Outdoors

View

Living Area

Bedroom

Layout

Accessibility

Building characteristics

Pool and wellness

Transport

Reception services

Common areas

Entertainment and family services

Cleaning services

Business facilities

Shops

Miscellaneous

Bath/Hot spring

Hostel facilities

Safety & security

Your sustainability practices

Safety features

Hygiene

Physical distancing

Cleanliness & disinfecting

Food & drink safety

Self check-in

Exclusive services